Main
Byron C. Jaeger
I am an Assistant Professor of Biostatistics. I work in the School of Public Health at the University of Alabama at Birmingham.
My research focuses on describing the role of diurnal (night-time) blood pressure patterns in developing cardiovascular disease and building predictive algorithms that can be used to support clinical decision-making.
Education
PhD, Biostatistics
Gilling’s School of Global Public Health
Chapel Hill, North Carolina
2017 - 2012
- Thesis: Extending R-squared to the Generalized Linear Mixed Model
- Honors: Recipient of ENAR Distinguished Student Paper Award
BS, Mathematics
Furman University
Greenville, South Carolina
2012 - 2008
- Thesis: Modeling three-dimensional pathways for the Tsunami Bar
- Honors: Recipient of DeLany Medal for Excellence in Mathematics
Professional Experience
Assistant Professor of Biostatistics
University of Alabama at Birmingham
Birmingham, Alabama
Present - 2017
- Investigating mechanisms of cardiovascular disease and hypertension
- developing machine learning algorithms to identify who may benefit from initiating antihypertensive medications
Adjunct Professor of Statistics
North Carolina Central University
Durham, North Carolina
2017 - 2016
Undergraduate and graduate instructor in biostatistics and statistical learning
Graduate Teaching Assistant
Gilling’s School of Global Public Health
Chapel Hill, North Carolina
2017 - 2014
- Intro to Biostatistics and Longitudinal Data Analysis
- Statistics Tutor, School of Nursing
Graduate Research Assistant
Gilling’s School of Global Public Health
Chapel Hill, North Carolina
2017 - 2012
Teaching Experience
General Linear Models
University of Alabama at Birmingham
N/A
Present - 2019
- Students are introduced to matrix algebra and theory supporting the general linear model.
- Students develop expertise in predictive modeling and statistical inference based on general linear models.
Statistical Programming with R
University of Alabama at Birmingham
N/A
Present - 2017
- Students develop core competencies in data analysis (import, clean, transform, visualize, and tabulate) using
R. - Course structure promotes interactive lectures and group exercises.
- Final exam: a comprehensive research project using
R markdown.
Statistical Software
tibbleOne
Convenient framework to tabulate participant characteristics.
N/A
2019
- Github Repository with ReadMe
- Total downloads as of 2020-01-26: 895
- Total citations: 0
obliqueRSF
Fit and interpret oblique random survival forests
N/A
2018
- GitHub Repository with ReadMe
- Total downloads as of 2020-01-26: 3,552
- Total citations: 0
r2glmm
Compute model and semi-partial R-squared for mixed models
N/A
2016
- GitHub Repository with ReadMe
- Total downloads as of 2020-01-26: 15,503
- Total citations: 72
Publications
Development of Predictive Equations for Nocturnal Hypertension and Nondipping Systolic Blood Pressure
BC Jaeger, JN Booth III, M Butler, LJ Edwards, …
Journal of the American Heart Association, 9 (2), e013696
N/A
2020
Citations: 0
Wearable Technology To Reduce Sedentary Behavior And CVD Risk In Older Adults: A Pilot Randomized Clinical Trial
LM Roberts, BC Jaeger, LC Baptista, SA Harper, …
Clinical Interventions in Aging, Volume 2019:14 Pages 1817-1828
N/A
2019
Citations: 0
Oblique Random Survival Forests
BC Jaeger, DL Long, DM Long, M Sims, JM Szychowski, …
Annals of Applied Statistics, 3 (2019), 1847-1883
N/A
2019
Citations: 0
Prediabetes and Risk for Cardiovascular Disease by Hypertension Status in Black Adults: The Jackson Heart Study
D Hubbard, LD Colantonio, AP Carson, S Sakhuja, BC Jaeger, …
Diabetes Care, c191074
N/A
2019
Citations: 3
Associations of awake and asleep blood pressure and blood pressure dipping with abnormalities of cardiac structure: The CARDIA study
NA Bello, BC Jaeger, JN Booth., M Abdalla, DE Anstey, …
Journal of Hypertension, epub
N/A
2019
Citations: 0
Prevalence of Activity Limitations and Association with Multimorbidity Among US Adults 50 to 64 Years Old
CB Bowling, L Deng, S Sakhuja, MC Morey, BC Jaeger, P Muntner
Journal of general internal medicine, pages 1-7
N/A
2019
Citations: 0
Association of Daytime and Nighttime Blood Pressure With Cardiovascular Disease Events Among African American Individuals
Y Yano, RM Tanner, S Sakhuja, BC Jaeger, …
JAMA cardiology, 4 (9), 910-917
N/A
2019
Citations: 0
Association of Region and Hospital and Patient Characteristics with Use of High-Intensity Statins after Myocardial Infarction among Medicare Beneficiaries
V Bittner, LD Colantonio, Y Dai, M Woodward, BC Jaeger, …
JAMA Cardiology, 4 (9), 865-872
N/A
2019
Citations: 1
Sex Differences in Masked Hypertension: The Coronary Artery Risk Development in Young Adults Study
DN Pugliese, JN Booth III, L Deng, DE Anstey, BC Jaeger, …
Journal of Hypertension, epub
N/A
2019
Citations: 0
Blood-Flow Restriction Resistance Exercise for Older Adults with Knee Osteoarthritis: a Pilot Randomized Clinical Trial
SA Harper, LM Roberts, AS Layne, BC Jaeger, AK Gardner, …
Journal of Clinical Medicine, 8 (2), 265
N/A
2019
Citations: 2
Multimodal Intervention to Improve Functional Status in Hypertensive Older Adults: a Pilot Randomized Controlled Trial
LC Baptista, BC Jaeger, SD Anton, AA Bavry, EM Handberg, …
Journal of Clinical Medicine, 8 (2), 196
N/A
2019
Citations: 2
Race and Sex Differences in Asleep Blood Pressure: The Coronary Artery Risk Development in Young Adults (CARDIA) Study
JN Booth, DE Anstey, NA Bello, BC Jaeger, DN Pugliese, …
The Journal of Clinical Hypertension, 21 (2), 184-192
N/A
2019
Citations: 3
An R-squared Statistic for Covariance Model Selection in the Linear Mixed Model
BC Jaeger, LJ Edwards, MJ Gurka
Journal of Applied Statistics, 46 (1), 164-184
N/A
2019
Citations: 2
ENAR Distinguished Student Paper Award
Out-of-Clinic Sympathetic Activity is Increased in Patients with Masked Uncontrolled Hypertension
M Siddiqui, EK Judd, BC Jaeger, H Bhatt, T Dudenbostel, B Zhang, …
Hypertension, 73 (1), 132-141
N/A
2019
Citations: 7
CVD and Mortality in Adults Aged 60+ Years According to Recommendations by the ACC/AHA and ACP/AAFP
BC Jaeger, DE Anstey, AP Bress, JN Booth III, M Butler, D Clark III, …
Hypertension, 73 (2), 327-334
N/A
2019
Citations: 2
Low Agreement Between Modified-Schwartz and CKD-EPI eGFR in Young Adults: a Retrospective Longitudinal Cohort Study
M Webster-Clark, BC Jaeger, Y Zhong, G Filler, A Alvarez-Elias, …
BMC Nephrology, 19 (1), 194
N/A
2018
Citations: 1
Assessing Responsiveness over Time of the PROMIS Pediatric Symptom and Function Measures in Cancer, Nephrotic Syndrome, and Sickle Cell Disease
BB Reeve, LJ Edwards, BC Jaeger, PS Hinds, C Dampier, DS Gipson, …
Quality of Life Research, 27 (1), 249-257
N/A
2018
Citations: 13
An R-squared Statistic for Fixed Effects in the Generalized Linear Mixed Model
BC Jaeger, LJ Edwards, K Das, & PK Sen
Journal of Applied Statistics, 44 (6), 1086-1105
N/A
2017
Citations: 96
Responsiveness of PROMIS Pediatric Measures to Hospitalizations for Sickle Pain and Subsequent Recovery
C Dampier, BC Jaeger, HE Gross, V Barry, L Edwards, Y Lui, …
Pediatric Blood & Cancer, 63 (6), 1038-1045
N/A
2016
Citations: 34
Enumerating Graph Depletions
BC Jaeger & TM Lewis
Online Journal of Analytic Combinatorics, 9, 1-17
N/A
2014
Citations: 0
Presentations
Novel 24-Hour Blood Pressure Profile in Patients with Resistant Hypertension
M Siddiqui, BC Jaeger, E Judd, T Dudenbostel, DM Pollock, ….
Journal of the American College of Cardiology, 73 (9 Supp. 1), 1818
N/A
2019
Citations: 0
Wearable Technology to Reduce Sedentary Behavior and Cvd Risk in Older Adults: a Pilot Trial
LM Roberts, BC Jaeger, LC Baptista, SA Harper, E Jackson, …
Medicine & Science in Sports & Exercise, 51 (6), 1004
N/A
2019
Citations: 0
Young Adult Risk Factor Burden and Sleep Hypertension in Middle-Age: the Coronary Artery Risk Development in Young Adults Study
JN Booth III, JE Schwartz, N Allen, BC Jaeger, CE Lewis, …
Circulation, 139 (Supp. 1), AP181
N/A
2019
Citations: 0
Change in Metabolic and Inflammatory Biomarkers after a 24-Week Multimodal Intervention
LC Baptista, BC Jaeger, SD Anton, AA Bavry, EM Handberg, …
9th International Conference on Frailty & Sarcopenia Research, Miami, FL
N/A
2019
Citations: 0
Oblique Random Survival Forests
BC Jaeger, DL Long, DM Long, M Sims, J Szychowski, Y Min, …
ICSA Applied Statistics Symposium, Raleigh, NC
N/A
2019
Citations: 0
Prolonged Hospital Length Of Stay After Pediatric Heart Transplantation And Its Impact On Outcomes: A PHTS Database Analysis
D Gupta, BC Jaeger, R Cantor, D Koehl, N Bansal, …
AHA Scientific Sessions, Philadelphia, PA
N/A
2019
Citations: 0
Improving mortality predictions for mechanical-circulatory-support-patients using follow-up data and machine learning
BC Jaeger, RS Cantor, R Rudraraju
AHA Scientific Sessions, Philadelphia, PA
N/A
2019
Citations: 0
An R-squared Statistic for Covariance Model Selection in the Linear Mixed Model
BC Jaeger, LJ Edwards, & MJ Gurka
ENAR Spring Meeting, Atlanta, GA
N/A
2018
Citations: 0
An R-squared Statistic for Covariance Model Selection in the Linear Mixed Model
BC Jaeger, LJ Edwards, & MJ Gurka
Joint Statistical Meeting, Vancouver
N/A
2018
Citations: 0
Current Support
Incorporation of a Hypertension Working Group into the Jackson Heart Study
University of Alabama at Birmingham
N/A
Present - 2017
- NHLBI R01 HL117323
- Primary Investigators: Muntner P., Shimbo D. & Gbenga O.
- Objective: identify novel risk factors for hypertension and potential approaches to improve hypertension control rates and reduce blood pressure related complications among African Americans.
- Roles: Co-Investigator & Lead Statistician
- Effort: 2.4 Calendar
Strategically Focused Hypertension Research Center
University of Alabama at Birmingham
N/A
Present - 2017
- AHA 15SFRN2390002
- Primary Investigators: Muntner P., Pollock J., & Calhoun D.
- Objective Evaluate racial differences in nocturnal hypertension and non-dipping blood pressure.
- Role: Co-Investigator & Lead Statistician
- Effort: 2.4 Calendar
Resveratrol and Exercise to Treat Functional Limitations in Late Life
University of Alabama at Birmingham
N/A
Present - 2017
- NIH/NIA 7R21AG049974
- Primary Investigators: Buford T.
- Objective: Evaluate the potential of two doses of resveratrol for improving the efficacy of physical exercise in treating age-related functional limitations.
- Role: Co-Investigator & Lead Statistician
- Effort: 0.24 Calendar
Improving Detection of Masked Hypertension: Analysis of Pooled Population and Community-Based Studies
Duke University
N/A
Present - 2018
- NIH/NHLBI 1R01HL144773
- Primary Investigators: Yano Y.
- Objective: determine how best to define masked hypertension and who should be screened for masked hypertension in the US population
- Role: Co-Investigator & Lead Statistician
- Effort: 0.6 Calendar
Machine Learning for Predicting Mechanical Circulatory Support Outcomes
University of Alabama at Birmingham
N/A
Present - 2018
- AHA 18AIML34280052
- Primary Investigators: Rudraraju R & Cantor R.
- Objective: comprehensive training and comparison (in terms of accuracy) of machine learning algorithms applied to mechanical circulatory support data.
- Role: Co-Investigator & Lead Statistician
- Effort: 0.6 Calendar
Data Warehousing Center Agreement for the Intermacs Databases
University of Alabama at Birmingham
N/A
Present - 2017
- STS HHSN268201100025C
- Primary Investigators: Kirklin J.
- Objective: develop a data and analytics driven decision support tool for patients with ambulatory advanced heart failure who are faced with the challenging options of implantation of a long term mechanical circulatory support device versus continued medical therapy despite ongoing significant functional limitation.
- Role: Co-Investigator & Lead Statistician
- Effort: 1.8 Calendar
Grants Submitted
Establishing Medicare Based Estimation for Cardiovascular Disease (EMBED)
Primary Investigator: Jaeger, Byron C.
N/A
2019
- Submitted to NIH - National Institutes of Health/DHHS
- Pending
Decoding Human Movements with Cortical and Subcortical Field Potentials with Directional DBS for Parkinson’s Disease
Primary Investigator: Walker, Harrison
N/A
2019
- Submitted to NIH - National Institutes of Health/DHHS
- Withdrawn
Non-Traditional Blood Pressure Parameters from Ambulatory Blood Pressure Monitoring and Left Ventricular Hypertrophy
Primary Investigator: Muntner, Paul M
N/A
2019
- Submitted to American Heart Association
- Pending
Determining True Versus Apparent Treatment-Resistant Hypertension among African Americans in the Jackson Heart Study
Primary Investigator: Tanner, Rikki M.D.
N/A
2019
- Submitted to National Heart, Lung, and Blood Institute/NIH/DHHS
- Pending, R01HL151687
Implementation and Accuracy of Blood Pressure Self-measurement in the Waiting Room
Primary Investigator: Muntner, Paul M
N/A
2019
- Submitted to National Heart, Lung, and Blood Institute/NIH/DHHS
- Pending, R01HL151609
Development of a Patient Decision Support Tool for Mechanical Circulatory Support
Primary Investigator: Kirklin, James K
N/A
2019
- Submitted to National Heart, Lung, and Blood Institute/NIH/DHHS
- Pending, R01HL151843
Home Versus Ambulatory Blood Pressure Monitoring and Falls in Older Adults
Primary Investigator: Muntner, Paul M
N/A
2019
- Submitted to Kaiser Foundation
- Pending
Resveratrol and Exercise to Enhance Mitochondrial Function in Older Adults
Primary Investigator: Buford, Thomas
N/A
2019
- Submitted to National Institute on Aging/NIH/DHHS
- Pending, F32AG066276
Automated Clinic Blood Pressure Assessment and Detection of White Coat and Masked Hypertension Study
Primary Investigator: Muntner, Paul M
N/A
2019
- Submitted to Columbia University
- Pending
NRT-HDR Where Health Meets Data: Training Biostatisticians for the World of Big Health Data
Primary Investigator: Cofield, Stacey S
N/A
2019
- Submitted to NSF - National Science Foundation
- Pending
Building and InnovatinG: Digital heAlth Technology and Analytics (BIGDATA) - Methodologic Core
Primary Investigator: Redden, David T
N/A
2019
- Submitted to NIH - National Institutes of Health/DHHS
- Pending
Building and Innovating: Digital Health Technology and Analytics (BIG DATA)
Primary Investigator: Curtis, Jeffrey R
N/A
2019
- Submitted to National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
- Pending, P30AR072583
Acute Renal Injury Sequela In NICU Graduates (ARISING)
Primary Investigator: Askenazi, D.
N/A
2018
Submitted to: NIH NIDDK, U34 DK117128-01A1
Associations of daytime and nighttime blood pressure measured via home versus ambulatory blood pressure monitoring with cardiac structure and function in African Americans
Primary Investigator: Yano, Y., & Muntner P.
N/A
2018
Submitted as ancillary study to: Jackson Heart Study
White coat hypertension with unattended versus attended blood pressure measurement
Primary Investigator: Abdallah M., Shimbo D., & Muntner P.
N/A
2018
Submitted as ancillary study to: Jackson Heart Study, 1R01HL146636-01
PRedictive mEthods for Decisions to Initiate or esCalate treatment for cardiovascular disease (PREDICT CVD)
Primary Investigator: Jaeger, B.
N/A
2018
Submitted as KL2 award to: Coordinating Center for Translational Science
Home Blood Pressure and Falls Among Older Adults
Primary Investigator: Muntner, Paul M
N/A
2018
- Submitted to National Heart, Lung, and Blood Institute/NIH/DHHS
- Active, R01HL147601
Automated Clinic Blood Pressure Assessment and Detection of White Coal and Masked Hypertension Study
Primary Investigator: Muntner, Paul M
N/A
2018
- Submitted to Columbia University
- Resubmitted
Incorporation of a Hypertension Working Group into the Jackson Heart Study
Primary Investigator: Muntner, Paul M
N/A
2016
- Submitted to National Heart, Lung, and Blood Institute/NIH/DHHS
- Active, R01HL117323
Guest Lectures
Reproducible reports with R
BST 655, KIRSO statistical lecture
N/A
2019
- Applied example using data from the titanic cruise
- Students were introduced to tibbleOne and rpriori packages
Using linear models for prediction
BST 655, BST 623
N/A
2019
- Applied example using housing price data
- Students introduced to bias-variance tradeoff and resampling
Introduction to Machine Learning
CCTS Friday Fellows talk, KIRSO statistical lecture, UAB SOPH programming group
N/A
2019
- Covers core principals in machine learning
- Applied examples using data from the Interagency registry for mechanically assisted circulatory support
Mentorship
Natalie Simpkins
Honors Thesis committee member
N/A
Present - 2019
Science and Technology Honors Program
Anastasia Hartzes
Dissertation committee member
N/A
Present - 2019
- Doctorate in Biostatistics
- Anastasia is preparing for her final exam
Steve Ampah
Dissertation co-advisor
N/A
Present - 2018
- Doctorate in Biostatistics
- Steve has passed his preliminary exam and is progressing towards graduation
Jeremiah Rastegar
BST 698
N/A
Present - 2019
- Jeremiah completed online and hands-on training in machine learning
- Applied work included predictive modeling using the INTERMACS data registry
John Bassler
Graduate research assistant
N/A
Present - 2019
- John has lead an analysis of the RESTORES trial data with Tom Buford
- A shiny application is being developed to disseminate this research
Nora Ahmad Mohammad Balas
Dissertation committee member
N/A
2019 - 2018
- Masters in Public Health
- Factors associated with breast cancer screening behaviors in a sample of Jamaican women
Andrew Sims
Academic Advisor
N/A
2019 - 2018
Assistance and advise with course registration and progression through graduate program
Catherine Jones
Dissertation committee member
N/A
2018 - 2017
- Masters in Epidemiology
- The association between physical activity and executive functioning in obese adults
Peer-Review
Reviewer
Peer-reviewed journal articles
N/A
Present - 2017
- Journal of the American Society of Nephrology
- Hypertension Research
- Mayo Clinic
- Circulation: Cardiovascular Quality and Outcomes
- Biometrics
Statistical reviewer
Jackson Heart Study
N/A
Present - 2017
Perform reviews of manuscript proposals, abstracts, posters, and manuscripts
Continuing Education
Applied Predictive Analytics
Max Kuhn
Austin, TX
2019
2-day short course
Regression Modeling Strategies
Frank Harrell
New Orleans, LA
2019
8-hour short course
Tidy Tools Workshop
Hadley Wickham
Atlanta, GA
2019
2-day short course
Joint longitudinal and survival analysis
Dimitri Rizoupolos
Atlanta, GA
2018
8-hour short course
Data Science Workflows Using R and Spark
Rick Peterson
Vancouver
2018
8-hour short course
Statistical Machine Learning for Biomedical Data
Noah Simon
Vancouver
2018
8-hour short course